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Peyton Elizabeth Lee will play the title role in Disney+’s female-led Doogie Howser reboot

Andi Mack star Peyton Elizabeth Lee will play the title role in the gender-swapped Doogie Howser reboot for Disney+

Disney announced Thursday that Peyton Elizabeth Lee will be putting on the white lab coat and stethoscope in Disney+’s upcoming reboot of Doogie Howser, M.D.

The 16-year-old actress will take over the position played by Neil Patrick Harris in the original ABC series, which ran from 1989 to 1993. 

This is the highest profile role to date for Lee, who previously played the title role in the Disney Channel original series Andi Mack. 

New face: Peyton Elizabeth Lee, 16, will star in a female-led reboot of Doogie Howser for Disney+, retitled Doogie Kameāloha, M.D.; seen in 2019 in Hollywood

The new half-house medical series has been transplanted to Hawaii and will be retitled Doogie Kameāloha, M.D., to reflect the character’s background.

Later on Thursday, Deadline reported that Episodes actress Kathleen Rose Perkins would also be joining the series in a lead role. 

In the rebooted series, Lee will play the 16-year-old doctor Lahela “Doogie” Kameāloha.

The mixed-race teen has to balance her social life with the commitments of a high-pressure medical career.

Old school: Neil Patrick Harris played the title character in the original series, which ran from 1989–1993, as a 16-year-old doctor. Lee's character has been renamed Lahela “Doogie” Kameāloha; publicity still for Doogie Howser, M.D.

Old school: Neil Patrick Harris played the title character in the original series, which ran from 1989–1993, as a 16-year-old doctor. Lee’s character has been renamed Lahela “Doogie” Kameāloha; publicity still for Doogie Howser, M.D.

Major part: Episodes actress Kathleen Rose Perkins would also be joining the series as Lahela's 'spit-fire' Irish mother, who's also a doctor and her supervisor at the hospital; seen in 2017

Major part: Episodes actress Kathleen Rose Perkins would also be joining the series as Lahela’s ‘spit-fire’ Irish mother, who’s also a doctor and her supervisor at the hospital; seen in 2017

Perkins will star as Lahela’s ‘spit-fire’ Irish mother, who is also a doctor and her supervisor at the hospital.

She also has a Hawaiian ‘Local Boy’ father who struggles to accept that his daughter is soon to be an adult.

Leading the rebooted series will be Executive Producer Kang, who previously worked with Perkins on ABC’s Fresh Off The Boat.

In the original series, which was created by the late Steven Bochco and David E. Kelley, Doogie’s father was a doctor, while he had a stay-at-home mother.

The new reboot will stay in the family, as Bochco’s widow Dayna Bochco and their son Jesse Bochco will executive produce the series with Kang, Jake Kasdan and Melvin Mar.

Strong start: Lee was part of a history-making cast during her three-season run on Disney's Andi Mack. She played the title character, who learned at the start of the series that her older sister was actually her mother

Strong start: Lee was part of a history-making cast during her three-season run on Disney’s Andi Mack. She played the title character, who learned at the start of the series that her older sister was actually her mother

Making strides: The series was the first on the Disney Channel to feature a gay main character; publicity still from Andi Mack

Making strides: The series was the first on the Disney Channel to feature a gay main character; publicity still from Andi Mack

Lee was part of a history-making cast during her three-season run on Disney’s dramedy Andi Mack.

She played the title character, who learned at the start of the series that her traveling older sister was actually her mother.

Andi Mack was the first Disney Channel series to feature a gay main character.

Joshua Rush played Andi’s friend Cyrus, who came out as gay in the show’s second season after developing a crush on the same boy Andi was interested in.

Off camera, Lee has a recurring voice role on Disney’s The Lion Guard, and she previously appeared on the now-canceled ABC crime series Stumptown. 

Burgeoning career: Off camera, Lee has a recurring voice role on Disney's The Lion Guard, and she previously appeared on the now-canceled ABC crime series Stumptown; seen with Skylar Astin in 2019

Burgeoning career: Off camera, Lee has a recurring voice role on Disney’s The Lion Guard, and she previously appeared on the now-canceled ABC crime series Stumptown; seen with Skylar Astin in 2019

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