Mikel Arteta is set to ring in the changes when he takes his Arsenal side to face Dundalk in the Europa League.
The Gunners were beaten 2-0 by Jose Mourinho’s table-topping Tottenham side in a disappointing match for Arteta.
His side now sit in 15th place in the Premier League table, and are seeing the gap increase between themselves and the teams fighting it out for top-six places.
In Europe, however, it’s been a different story for Arsenal, with five wins from their opening five group games.
They face Dundalk tonight having already won the group, and as a result Arteta will likely give some of his more senior players a rest.
In goal, Runar Alex Runnarsson will likely start to give Bernd Leno the chance to recover ahead of the weekend’s crucial game against Burnley.
In defence, Arteta will likely play a flat back four with Cedric Soares at right-back, Saed Kolasinac at left-back and Shkodran Mustafi and Callum Chambers in the middle.
He will likely play a 4-2-3-1 formation, with Ainsley Maitland-Niles and Mohamed Elneny as the two midfielders behind an attacking trio of Nicolas Pepe, Emile Smith-Rowe and Reiss Nelson.
Eddie Nketiah put in a solid performance against Rapid Vienna and will lead the line again tonight.
Alexandre Lacazette also enjoyed a good showing against Vienna, but then struggled when he played 90 minutes against Tottenham over the weekend.
For that reason, the French striker will drop down to the bench in order to recover and go again this weekend when Arsenal face Burnley.
Speaking ahead of the game, Arteta confirmed he was preparing to rotate his side heavily in order to cope with the congested fixture crisis.
“We have a few kids here. We left a few players at home as well,” he said.
“There are a lot of games and we need a complete training week as well, which I think is going to benefit us. But we’re still going to have a very competitive team to play tomorrow.
Arsenal predicted line-up (4-2-3-1): Runarsson; Cedric, Mustafi, Chambers, Kolasinac; Maitland-Niles, Elneny; Pepe, Smith-Rowe, Nelson; Nketiah