Bayern Munich have confirmed that Robert Lewandowski will face a four week injury lay off.
It means their star striker is out of their Champions League quarter-final tie with Paris Saint-Germain.
The European champions have confirmed that their leading scorer will face four weeks on the sidelines with strained knee ligaments.
It means he will miss the last eight showdown with PSG, in a repeat of last season’s final, as the Bavarians target successive European triumphs.
Maxim Choupo-Moting, hero of PSG’s quarter-final comeback vs Atalanta last season, could now lead Bayern’s attack at the Allianz Arena next Wednesday following his summer move.
Serge Gnabry is another option for Bayern boss Hansi Flick.
Bayern will host the French champions on April 7 before heading to Paris six days later.
A Bayern statement said: “Robert Lewandowski has suffered sprained ligaments in his right knee. The striker will be out for around four weeks.”
The Pole suffered a knee injury during his country’s win over Andorra at the weekend.
Initial scans on Monday morning suggested that the injury may not have been as bad as first feared.
But after returning to Bavaria and undergoing further tests, the injury is more severe than first thought.
It is a major blow to Lewandowski’s chances of breaking Gerd Muller’s single season record in the German top flight.
Lewandowski has scored 42 times in just 36 matches, with 35 of those coming in the Bundesliga.
Muller’s record, set in 1972, stands at 40.
Five of Lewandowski’s strikes have come in Europe with the Pole netting in each leg of their last 16 win over Lazio.