Nuno Espirito Santo will attempt to inject some life into his ailing Spurs side tonight when they travel to Turf Moor.
A 1-0 reverse at West Ham made it two consecutive defeats after the manager had rested his favoured starting XI for the loss in Vitesse just days earlier, leading to big questions over who will play against Burnley.
The Clarets are hoping to reach the Carabao Cup quarter-finals for the first time since 2008/09, when as a Championship club they were knocked out of the semis by Tottenham.
Spurs have been something of a bogey club for Burnley in recent times, grabbing nine wins and four draws in their last 14 meetings.
A 2-2 draw at Southampton on the weekend sends Sean Dyche’s team into this game on difficult form, with only one win in 90 minutes all campaign and still without a victory in the league.
With kick-off at 7.45pm, follow all the action with Dan Kilpatrick at Turf Moor…
Tottenham predicted XI: Gollini; Tanganga, Sanchez, Romero, Reguilon; Lo Celso, Skipp; Bergwijn, Ndombele, Gil; Kane.
Nuno gave his second-string a chance to impress in Arnhem and they failed to take it, but with a crunch meeting with Manchester United to come at the weekend, he may not be too keen on fielding a full strength line-up either.
A hybrid side is the most likely alternative, though Dele Alli and Harry Winks have both been omitted from the squad, raising further doubts over their respective Spurs futures.
Matt Doherty is set to return, but Ryan Sessegnon remains out.
How to watch
The match will not be broadcast live on TV in the UK.
However, highlights are available on Quest from 10:30pm BST.
Welcome to another huge game for Nuno Espirito Santo’s Tottenham as they travel to Burnley in the Carabao Cup.
It may not be the most important competition for either side but neither would say no a trophy, or a vital win after rocky spells of form.
Team news is due in about an hour and we’ll keep you up to date with all the pre-game goings on beforehand.