United looked to have drawn a group of death with PSG and RB Leipzig in Group H, but the Red Devils beat both sides in their opening two fixtures to become heavy favourites to qualify for the knockout stages.
However, consistency has been a problem for United, and they lost 2-1 to Basaksehir in Turkey on matchday three to blow the group wide open again.
United’s Premier League rivals Chelsea are also playing this evening, and can seal qualification to the last-16 with victory over Rennes in France.
Elsewhere, a struggling Barcelona head to Dynamo Kyiv looking for a result, while Borussia Dortmund will hope that Erling Haaland continues his sensational form as BVB face Club Brugge.
Champions League fixtures tonight
5:55pm | Krasnodar vs Sevilla, Rennes vs Chelsea
8:00pm | Juventus vs Ferencvaros, Dynamo Kyiv vs FC Barcelona, PSG vs RB Leipzig, Man United vs Istanbul Basaksehir, Lazio vs Zenit, Borussia Dortmund vs Club Brugge
Follow all the action on our LIVE match blog below…
Hello and welcome to our LIVE match coverage of Tuesday’s Champions League action!