A Cup holders Arsenal crashed out of the competition in the fourth round on Saturday as Southampton beat the Gunners 1-0 at St Mary’s.
The Saints will now face Wolves, who beat non-League Chorley on Friday night, for a place in the quarter-finals.
The game of the fourth round sees Manchester United and Liverpool face off for a fifth-round tie against West Ham, eight days on from a dire Premier League encounter, Chelsea welcome Luton and Fulham host Burnley.
Man City avoided a shock as they fought back from a goal down to win 3-1 at League Two Cheltenham on Saturday. Tottenham head to Wycombe to conclude the weekend on Monday night.
FA Cup fourth round draw in full
Swansea 5-1 Nottingham Forest
Manchester United vs Liverpool
Cheltenham Vs Man City, Fa Cup Preview
Millwall 0-3 Bristol City
Brighton 2-1 Blackpool
Wycombe Vs Tottenham, Jose Mourinho Press Conference
Sheffield United 2-1 Plymouth
Everton vs Sheffield Wednesday
Frank Lampard gives spiky responses to questions on Chelsea’s struggles
FA Cup fifth round draw in full
Fulham/Burnley vs Bournemouth/Crawley
Manchester United/Liverpool vs West Ham
Sheffield United vs Bristol City
Barnsley vs Chelsea/Luton
Everton/Sheffield Wednesday vs Wycombe/Tottenham
Swansea vs Cheltenham/Man City
Brentford/Leicester vs Brighton