Bale changed the game from the bench in last weekend’s defeat to West Ham before scoring against Wolfsberger again on Wednesday, and the Wales forward is rewarded.
Dele Alli was also impressive in the Europa League round-of-32 second leg, scoring a brilliant bicycle kick and getting two assists, but an appearance from the bench seems more likely for the 24-year-old as he is still working his way back to fitness.
Lucas Moura is also rewarded for a goal against the Hammers with another start at No10. Erik Lamela is on the bench.
Tottenham: Lloris, Aurier, Sanchez, Alderweireld, Reguilon, Ndombele, Hojbjerg, Bale, Lucas Moura, Son, Kane
Subs: Doherty, Winks, Lamela, Hart, Dier, Sissoko, Alli, Davies, Vinicius
Burnley: Pope, Lowton, Tarkowski, Mee, Taylor, Brownhill, Cork, Westwood, McNeil, Rodriguez, Vydra
Subs: Wood, Peacock-Farrell, Stephens, Bardsley, Long, Dunne, Richardson, Benson, Driscoll-Glennon
Venue: Tottenham Hotspur Stadium, Sunday 28 February, 14.00, Sky Sports
Spurs squad from: Lloris, Hart, Whiteman, Aurier, Tanganga, Doherty, Reguilon, Davies, Sanchez, Alderweireld, Dier, Rodon, Hojbjerg, Ndombele, Sissoko, Winks, Dele, Bergwijn, Lamela, Bale, Lucas, Son, Kane, Vinicius.
Last meeting: Burnley 0-1 Spurs (Son)