The Serbian striker has already scored for the club following his major money move from bitter rivals Fiorentina last month but is yet to test himself in Europe’s elite competition.
One of the most exciting young forwards in Europe, it will be fascinating to see how he takes to the challenge, particularly after Kylian Mbappe and Erling Haaland enhanced their reputations within it.
Elsewhere, Max Allegri has a strong squad from which to choose and comes into this game in relatively good form.
While Juventus certainly haven’t hit the heights of previous campaigns, they are unbeaten in six Serie A games and won their first four Champions League outings.
Juventus predicted XI (4-4-2): Szczesny, Danilo, Chiellini, De Ligt, Sandro; Cuadrado, Locatelli, Zakaria, Rabiot; Morata, Vlahovic
Kick-off time: 8pm GMT, Tuesday 22 February
Venue: Estadio de la Cerámica, Villarreal
TV channel: BT Sport 3
Doubts: Dybala, Bonucci