Sterling picked up a calf injury during England training but is hopeful of being fit, while Aguero used the international break to regain some fitness.
Nathan Ake was another casualty of the domestic hiatus and should sit out the game.
There remains confusion over Oleksandr Zinchenko’s availability after the entire Ukraine squad was placed into quarantine.
Predicted Manchester City XI (4-3-3): Ederson; Walker, Dias, Laporte, Cancelo; De Bruyne, Rodri, Gundogan; Torres, Jesus, Foden
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