Conte has a decision to make at right wing-back, where Emerson Royal and Matt Doherty now face competition from Kulusevski, who Conte believes could be an option in the role.
The Spurs manager must also pick between Lucas Moura and Steven Bergwijn for the third attacking spot after impressive displays from the Dutchman before the winter break.
Tottenham predicted XI: Lloris; Romero, Dier, Davies; Emerson, Winks, Hojbjerg, Reguilon; Lucas, Kane, Son.
Where: Tottenham Hotspur Stadium
When: Saturday, February 5, 8pm GMT
Referee: Stuart Attwell
Spurs squad from: Lloris, Gollini, Austin, Doherty, Emerson, Reguilon, Sessegnon, Davies, Romero, Dier, Rodon, Sanchez, Winks, Hojbjerg, Bentancur, White, Bergwijn, Lucas, Kulusevski, Son, Kane.
Injured: Skipp (groin), Tanganga (knee)