ucas Moura is back in contention for the north London derby.
Moura was substituted during last week’s Europa Conference League match at Rennes and then subsequently missed last Sunday’s 3-0 home defeat against Chelsea.
The Brazilian could play as part of a front three alongside Harry Kane and Heung-min Son.
Tottenham are still without Steven Bergwijn due to injury. Ryan Sessegnon is also sidelined.
Tottenham go into the game on the back of Wednesday’s Carabao Cup win over Wolves on penalties and some players, including Tanguy Ndombele, could start for a fourth time in ten days against Arsenal.
Nuno Espirito Santo has warned his players, who are at varying levels of fitness, must be careful.
“Each and every one of our players has to be really careful,” he said.
“We have to be really careful in how we decide and all these things, because we have different players in different momentums in terms of preparation.
“We have Lucas back which is good news so let’s try to make and prepare the game.”
Tottenham predicted XI (4-3-3): Lloris; Tanganga, Romero, Dier, Reguilon; Dele, Hojbjerg, Ndombele; Lo Celso, Kane, Son.