Arsenal manager Mikel Arteta is likely to make changes for the game in Norway and Luiz should come into the defence along with Ainsley Maitland-Niles, Cedric Soares and Shkodran Mustafi. Alex Runarsson could make a rare start in goal too.
Further forward, Nicolas Pepe should get the nod after travelling with the squad despite being sent off against Leeds. The Ivorian is suspended for the Premier League, but can play in Europe.
Joe Willock and Reiss Nelson will hope to get more minutes too, while Eddie Nketiah is pushing to get the nod over Alexandre Lacazette.
Arsenal predicted lineup (4-2-3-1): Runarsson; Cedric, Mustafi, Luiz, Maitland-Niles; Ceballos, Xhaka; Pepe, Willock, Nelson; Nketiah.
Arsenal squad from: Leno, Macey, Runarsson; Bellerin, Cedric, Gabriel, Holding, Luiz, Mustafi, Tierney; Azeez, Ceballos, Cottrell, Maitland-Niles, Smith Rowe, Willock, Xhaka; Aubameyang, Balogun, Nelson, Nketiah, Lacazette and Pepe.
Injured: Elneny (Covid-19), Kolasinac (Covid-19) Mari (ankle), Martinelli (knee), Partey (thigh), Saka (dead leg) and Willian (calf)