Top-four rivals Leicester visit the London Stadium today, with the Hammers also without Declan Rice, who has been captaining the side this season.
The England international suffered a knee ligament injury on international duty and there is no timescale for his return, though those within the medical department are optimistic that it could be around a month.
Moyes said: “He’s got an injury as everybody is aware, we will try to get him back as quickly as we can but we won’t put a timescale on it.”
Angelo Ogbonna has returned to training this week while Arthur Masuaku made his first start since early December at Wolves on Monday.
West Ham predicted XI (5-3-2): Fabianski; Coufal, Diop, Dawson, Cresswell, Masuaku; Noble, Soucek, Fornals; Lingard, Bowen
Sunday 2.05pm, Sky Sports
West Ham squad from: Fabianski, Martin, Randolph, Trott, Diop, Dawson, Alves, Balbuena, Coufal, Fredericks, Johnson, Cresswell, Noble, Soucek, Fornals, Lanzini, Lingard, Benrahma, Bowen, Odubeko
Unavailable: Antonio (hamstring), Rice (knee), Yarmolenko (knee)