Italy are already through to the last-16 and so Mancini could rotate his side, giving the likes of Marco Verratti important minutes ahead of the knockout phase, but knows his side still need a point to secure top spot and, in theory, a favourable draw in the next round.
Wales, meanwhile, are not yet certain of their place in the last-16 but it would tae an unlikely sequence of results for them to miss out and Page may opt to rotate anyway, with fears over the durability of some of his key players, such as Aaron Ramsey and Gareth Bale, because of their lack of club football this season.
Here is how we predict the two sides will shape up…
Italy vs Wales predicted lineups
Italy XI: Donnarumma; Di Lorenzo, Bonucci, Acerbi, Emerson; Verratti, Cristante, Barella; Bernardeschi, Belotti, Chiesa
Wales XI: Ward; Roberts, Mepham, Rodon, Gunter, Williams; Morrell, Allen; Bale, Wilson, James
Goalkeepers: Gianluigi Donnarumma, Alex Meret, Salvatore Sirigu
Defenders: Francesco Acerbi, Alessandro Bastoni, Leonardo Bonucci, Giorgio Chiellini, Giovanni Di Lorenzo, Emerson, Alessandro Florenzi, Leonardo Spinazzola, Rafael Toloi
Midfielders: Nicolo Barella, Bryan Cristante, Jorginho, Manuel Locatelli, Lorenzo Pellegrini, Stefano Sensi, Marco Verratti
Forwards: Andrea Belotti, Domenico Berardi, Federico Bernardeschi, Federico Chiesa, Ciro Immobile, Lorenzo Insigne, Giacomo Raspadori
Goalkeepers: Wayne Hennessey, Danny Ward, Adam Davies
Defenders: Connor Roberts, Neco Williams, Chris Gunter, Joe Rodon, Ethan Ampadu, Chris Mepham, Ben Cabango, Ben Davies, Rhys Norrington-Davies, Tom Lockyer
Midfielders: Joe Allen, Joe Morrell, Matthew Smith, Jonny Williams, Aaron Ramsey, Dylan Levitt, Rubin Colwill, Harry Wilson
Forwards: Daniel James, David Brooks, Tyler Roberts, Gareth Bale, Kieffer Moore