Leeds were poor in possession and defended badly as Leicester took full advantage on the counter-attack to win 4-1 at Elland Road.
Bielsa is without a couple of important players for the clash with Palace at Selhurst Park and Kalvin Phillips continues to recover from his shoulder injury.
Record signing Rodrigo is self-isolating after testing positive for coronavirus and should return after the international break.
Diego Llorente and long-term absentee Adam Forshaw are still out injured and Bielsa says he will make a late call on Brazilian winger Raphinha.
Expected return date: end of November
Phillips hurt his shoulder in the home defeat to Wolves last month when he inadvertently headed Raul Jimenez’s shot into his own net for the only goal.
Leeds claimed he could be out for up to six weeks, although Bielsa claims that timescale is not definite.
When asked for an update on Phillips’ progress this week, Bielsa said: “Phillips won’t be available for the game on Saturday.”
Leeds have had mixed results trying to replace Phillips in his specialist midfield holding role with Mateusz Klich.
Raphinha missed Monday’s home defeat to Leicester with an ankle injury and Bielsa claims he will make a late call on the Brazilian winger’s fitness.
Raphinha has just made two substitute appearances for Leeds since joining from Rennes and last figured in the fine win at Aston Villa.
Bielsa said: “I’ve not decided just yet. I’m going to wait until before the game to decide if it’s possible that we can count on him or not.”
Injury: groin strain
Expected return date: after the international break
Llorente is taking longer than expected to recover from the groin injury he suffered with Spain during the last international break.
He was hurt after winning his sixth camp against Portugal and has spent the last month receiving treatment at Thorp Arch.
The centre-half has still to make his Leeds debut following his move from Real Sociedad and Bielsa says he will not be ready for Palace.