The pair both come in at Old Trafford, with Sadio Mane dropping to the bench.
Joel Matip made his return from injury but is not ready for another game so soonupon, while James Milner comes in.
Alex Oxlade-Chamberlain was one of many poor showings against Burnley and drops out – and Curtis Jones has an opportunity to shine.
Liverpool lineup: Alisson, Alexander-Arnold, R. Williams, Fabinho, Robertson, Thiago, Wijnaldum, Milner, Jones, Salah, Firmino
Subs: Kelleher, Mane, Oxlade-Chamberlain, Minamino, Tsimikas, Shaqiri, Origi, Phillips, N. Williams
Injury list: Diogo Jota (knee), Virgil van Dijk (knee), Joe Gomez (knee), Naby Keita (knock), Jordan Henderson (muscular)