The Cameroon international seems certain to miss the clash with Newcastle on Wednesday, meaning either Nat Phillips or Rhys Williams will partner Fabinho at centre-back at St. James’ Park.
“Joel told me he felt something in his adductor, that’s obviously not too good,” Jurgen Klopp said.
“Not sure how serious it is now but it was serious enough that he had to leave the pitch.”
Klopp also confirmed that Naby Keita – only just back from injury – has suffered another muscle problem.
However, his midfield options are boosted with James Milner starting and Thiago Alcantara returning on the bench, while Alex Oxlade-Chamberlain continues to build towards full match sharpness having made a substitute appearance against West Brom.
However, the two dropped points against the Baggies, coupled with a three-day break – in comparison to many teams’ two – could prevent Klopp from making wholesale changes.
Liverpool XI: Alisson, Alexander-Arnold, Phillips, Fabinho, Robertson, Jones, Henderson, Milner, Salah, Firmino, Mane
Subs: Wijnaldum, Thiago, Oxlade-Chamberlain, Minamino, Shaqiri, Origi, Rhys Williams, Kelleher, Neco Williams