However, Adams returns to the fold on Saturday as Wales look to secure a Triple Crown and keep their Grand Slam bid alive, forming part of an exciting back three alongside Louis Rees-Zammit and Liam Williams, who shifts from wing to full-back with Leigh Halfpenny out.
There is a wealth of experience in the centres as George North wins his 100th senior cap alongside the returning Jonathan Davies.
Injured scrum-half Tomos Williams is replaced by Scarlets’ Kieran Hardy, who makes just his third Wales appearance against England.
Wales team to face England
L Williams; Rees-Zammit, North, J Davies, Adams; Biggar, Hardy; W Jones, Owens, Francis; Beard, AW Jones (c); Navidi, Tipuric, Faletau
Replacements: Dee, R Jones, Brown, Hill, Botham, G Davies, Sheedy, Halaholo
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