They host an RB Leipzig side facing an early exit following two defeats against Club Bruges and City. The Bundesliga team lost 6-3 at the Etihad Stadium on matchday one and then suffered a surprise 2-1 defeat at home to Club Bruges.
PSG will be without Neymar due to injury but millions around the world will tune in to watch Messi.
There is also plenty of intrigue around PSG this week after the French club were rocked by Mauro Icardi’s family drama. Icardi missed two days of training on the eve of the game after his wife Wanda Nara accused him of cheating on her.
Where to watch Man City vs Leipzig
TV channel: Tonight’s match will be televised on BT Sport 3, with coverage starting at 7.30pm.
Live stream: BT Sport subscribers will be able to watch the match online via the website or BT Sport app.