A superb opening victory at Twickenham got Scotland’s campaign off to the perfect start and they once again hold the Calcutta Cup, but they must now defy recent history.
In 2021 and 2022, Scotland beat England in their first Six Nations match before losing to Wales a week later, bringing an immediate halt to the momentum that had been picked up.
Gregor Townsend’s side will believe this is a Wales side there for the taking though, after they were beaten 34-10 by Ireland in Cardiff. Even Warren Gatland appears unable to turn their fortunes around in the short timeframe he’s been given.
Victory here for the Welsh would get things back on track, while Scotland will be desperate to arrive in Paris in a fortnight’s time right in the thick of the battle at the top of the standings.
Scotland vs Wales date, kick-off time and venue
Scotland vs Wales is the second Six Nations match on Saturday, after Ireland face France in a blockbuster clash earlier in the day.
The match is due to begin at 4.45pm GMT on, Saturday February 11, taking place at Murrayfield in Edinburgh.
How to watch Scotland vs Wales
TV channel: Scotland vs Wales is being broadcast live and free-to-air on BBC One, with coverage beginning at 4pm. Live coverage is also available on Welsh-language channel S4C from 4pm.
Live stream: Fans can also follow all the action as it happens live online via the BBC Sport website, BBC iPlayer or S4C Clic.
Scotland vs Wales team news
Scotland are boosted by the availability of Zander Fagerson and Hamish Watson, with the forwards both fit again after missing the Twickenham win over England.
“We have a lot of players in form in those positions so competition will be stiff in those departments,” said scrum coach Peter De Villiers.
Luke Crosbie played well against England but could make way for Watson, while Andy Christie is out of the squad with a dead leg.
Alun Wyn Jones is fit for Wales, despite initially being ruled out. Having initially failed a head injury assessment, the Welsh medical staff have now deemed it to be a neck injury with the lock showing no signs of concussion.
Tomas Francis is set to miss out after coming off against Ireland with a calf injury, but George North is expected to overcome the knocks he picked up last weekend.
Scotland vs Wales lineups
The lineups will be revealed on Thursday – check back in then for all the confirmed team news.
Scotland vs Wales head to head (h2h) history and results
Wales have enjoyed plenty of success over Scotland, winning 18 of the past 21 matches between the two sides.
Scotland wins: 50
Wales wins: 75
Scotland vs Wales prediction
A statement win followed by a stumbling performance has been a regular theme for Scotland, and their task is to ensure a hat-trick of wins over England is not followed by a hat-trick of defeats to Wales.
They can take plenty of confidence from their ruthless Twickenham display, while Townsend has insisted his side “can grow more” in the weeks ahead.
History is not necessarily on their side – Scotland have never won their first two matches of the Six Nations and they have never beaten Warren Gatland.
What is on their side is a Wales team that struggled badly in Cardiff last week, even if Ireland, the best team in the world, will prove far too good for most sides.
Gatland went for experience in the opening game, but a number of those trusted players looked to be past their best. This would arguably be the most disappointing of all the recent defeats Scotland have suffered to Wales, but they should be confident of coming out on top.
Scotland to win, by 10 points.
Scotland vs Wales odds
Scotland to win: 4/11
Wales to win: 12/5
Odds via Betfair (subject to change).