Ole Gunnar Solskjaer had previously hinted that youngster Joe Hugill was in line for his Manchester United debut before Amad.
The Ivorian came off the bench to make his first appearance for the Red Devils in their Europa League win over Real Sociedad on Thursday night.
Amad only arrived at the club in January having been allowed to remain at Atalanta for the first half of the season.
The teenager arrived with high expectations and hit the ground running with the U23s.
He scored twice, including a Panenka penalty, as United stuck six past rivals Liverpool – but it was Hugill who got the other four.
Hugill is also pushing for a first team spot and Solskjaer had suggested, based on that showing, that he would get an opportunity before Amad.
“We’re going to give him the time to settle in,” he said on Amad following his U23s outing.
“If we go from that game [vs Liverpool], I’d pick Joe Hugill.
“Four goals by Hugill, he’s a top striker as well, we’re looking forward to seeing his development.”
Hugill was signed from Sunderland for £300,000 last year and has already made an impression.
Solskjaer has been willing to give young players opportunities during his tenure with Mason Greenwood a clear example.
Amad’s brief cameo will now lead to questions as to when he will be handed his first start.
“We will make a decision after Newcastle (this weekend),” said the United boss.
“Couple of games in the reserves. Amad is getting closer. We will see how much game time we will get.”
The 18-year-old will provide competition for the wide roles in attack.
Despite remaining at Atalanta following his £38m signing Amad only played twice – both times from the bench.