It has been over a thousand days since the South African fans were able to attend a home game featuring their heroes, due to the Covid pandemic.
Many expect Wales to be brushed aside in this glorious homecoming run of three tests in the Southern Hemisphere.
But, with the altitude and history against them, the visitors are intent on earning a first-ever victory away to South Africa at the 11th attempt.
Here are all the details for tuning in..
Where to watch South Africa vs Wales
TV channel: In the UK, South Africa vs Wales is being broadcast live on Sky Sports Main Event and Sky Sports Action, with coverage beginning at 4pm BST and 3.30pm respectively before kick-off at 4.05pm.
Live stream: Subscribers can also watch the game unfold live online via the Sky Go app.