Ralph Hassenhutl’s side have made a terrific start to the season and even went top of the division a couple of weeks ago.
United, meanwhile, are looking to make it three successive wins in the Premier League for the first time this season after seeing off West Brom and Everton either side of the international break.
Ole Gunnar Solskjaer’s men also enjoyed a confidence-boosting win over Istanbul Basaksehir in midweek, taking a big step towards Champions League knockout qualification.
Southampton vs Man United is scheduled for a 2pm GMT kick-off on Sunday, November 29, 2020.
The match will be held behind closed doors at St. Mary’s.
TV channel: Saturday’s match will be televised on Sky Sports Main Event and Premier League, with coverage from 1pm.
Live stream: Sky Sports subscribers will be able to watch the match online via SkyGo and the Sky Sports app.
Ole Gunnar Solskjaer praises Manchester United’s form after rousing win against Istanbul Basaksehir
Southampton remain without Danny Ings and Nathan Redmond because of injury but Theo Walcott will be involved despite having broken a bone in his wrist.
Donny van de Beek could start in midfield, with both Paul Pogba and Scott McTominay expected to be unavailable.
Head to head (h2h) history and results
- Southampton wins: 28
- Man United wins: 65
- Draws: 34
- Last meeting: Man United 2-2 Southampton (July 13, 2020)
Bettings odds and tips (subject to change)
- Southampton win: 3/1
- Draw: 3/1
- Man United win: 11/10
This weekend get a £10 free bet with Betfair, when you bet £10 on a Same Game Multi on the Premier League.
Terms: Min £10 Same Game Multi bet on any EPL match this Fri – Sun. Free bet valid for 72 hours, awarded at bet settlement. Excludes cashed out bets. T&Cs apply.