The Ghanaian midfielder, who passed a late fitness test before the North London Derby, was attempting to limp off injured just seconds before Tottenham attacked.
Arteta tried to get Partey back into position but by that point Heung-min Son had teed up Harry Kane who thundered the hosts into a 2-0 lead.
Partey was subsequently substituted by Dani Ceballos.
“I can’t see exactly what’s happened but Thomas Partey has walked off the pitch and left them with that five v two, Gary,” Jamie Redknapp said on Sky Sports.
“That’s where the problem comes from. And to add salt to the wound he’s now had to come off, they’ve had to make a substitution into Ceballos.
“But that was the problem because he’s trying to come off the pitch and he’s not right and that’s what leaves them so exposed at the back.”
At half-time, Alex Scott slammed the midfielder.
“Even if you’ve got an injury you wait, you don’t leave your position,” she said. “The fact that Arteta is pushing you to get back in because you have left that space makes it easier for Tottenham to expose you how they have, how easily they have broken down Arsenal.”
“Big players, leaders don’t allow that to happen on the football pitch,” said Souness who then focussed more on Granit Xhaka.
“If he’s injured, he’s injured. He’s screaming at people.
“If you look at Xhaka, as a holding central midfield player, I don’t what Xhaka is, it’s been about six seven years – I’m not quite sure what he is, the alarm bells are ringing. We’re going forward, all the time looking over you’re shoulder where we’re vulnerable. They’re just empty.
“Lo Celso picks it up, on you go 2-0.”