Jurgen Klopp’s Premier League champions got the better of Spurs to climb back into the top four, while Mournho’s men are now four points adrift of the Champions League qualification places – and potentiallu facing another spell without Harry Kane.
Mane had been a thorn in the side of Spurs’ defence from the very first whistle, and finally made the breakthrough in first-half injury time as he broke the offside trap to tee up Roberto Firmino for a tap-in.
Spurs had chances at the other end in a frenetic opening 45 minutes: Heung-min Son seeing an early goal ruled out by VAR for a tight offside in the build-up, but it was Liverpool who went in ahead – and Spurs lost Kane to injury at the interval.
A blistering start to the second half saw Trent Alexander-Arnold give Liverpool a two-goal cushion which Pierre-Emile Hojbjerg quickly halved; Mo Salah then had a goal ruled out by VAR for a Firmino handball, but Mane volleyed Liverpool’s third 25 minutes from time to secure the result.
Mourinho had sprung a defensive surprise by naming Joe Rodon in a three-man back line, while Toby Alderweireld and Davinson Sanchez were both benched.
Jurgen Klopp was able to call on Jordan Henderson and Joel Matip, with the pair returning to slot in at centre-back.
With both managers naming make-shift defences, it was no surprise to see the two teams playing a more open game than expected – and Mane found plenty of joy in behind, stinging the hands of Hugo Lloris on two occasions and getting into pockets of space time and time again.
Liverpool made the breakthrough in the third of four minutes of first-half injury time after Kane twice suffered issues, and
There was more bad news for Tottenham as Kane was subbed off at the interval due to those injury concerns, but things quickly got worse for Spurs.
Lloris could only palm away a low Mane effort into the path of Alexander-Arnold, who duly drilled Liverpool two goals ahead two minutes after the restart.
Two goals behind and without their talisman, the game already seemed to be beyond Spurs – but a fantastic, swerving effort from Hojbjerg halved the defecit two minutes later.
Liverpool thought they had restored their two-goal advantage soon after as Mo Salah lashed home inside the box, but it was the champions’ turn to fall foul of VAR as the goal was chalked off for a handball by Firmino in the build-up.
That was a let-off for Spurs, but their failure to track Mane was again their downfall: Alexander-Arnold whipped in a hopeful cross from the right flank, and Joe Rodon failed to deal with the bouncing ball as he deflected it into the path of Mane – and he volleyed home the gift.