The crunch clash takes place on Saturday afternoon at the Johan Cruyff Arena in Amsterdam, with anticipation levels reaching fever pitch back in Wales.
It’s the second straight Euros that the Dragons have made it through to the knockout stages, having done the same five years ago in France.
That run culminated in a semi-final defeat to eventual champions Portugal and Wales fans will be dreaming of reaching the semi-finals again in this year’s pan-European competition.
First up, though, are a Denmark side who will also have the neutrals behind them following playmaker Christian Eriksen’s on-pitch cardiac arrest in their opening Group B match against Finland.
Eriksen has now thankfully been released from hospital as he continues his recovery, but will join many fans around the world in willing the Danes on to do well as the Euros after such a distressing incident.
It means while Wales will start as underdogs in Amsterdam, chances are few neturals will be cheering them on which is something Dragons defender Connor Roberts is aware of.
He told BBC Sport : “”It’s going to be really tough but hopefully we can win. I think 99% of the world are going to be supporting Denmark.
“It’s going to be tough but we’re a good team, we’ve got good players and we’ve got a little bit of momentum with good performances under our belts.
“They’re a really good team and they’re going to have a lot of support but, when we cross that white line, we just have to give everything.”
Wales made it through to the knockout stages after finishing second in Group A behind winners Italy, with Page’s men collecting four points from their three games.
Kieffer Moore’s goal helped the Welsh record a 1-1 draw in their opening match against Switzerland in Baku, despite being second-best for much of the match.
Goals from Aaron Ramsey and Roberts then secured a 2-0 win for Wales in their second match against Turkey in the capital of Azerbaijan, despite Bale missing a second-half penalty.
And though they were beaten 1-0 by Italy in Rome at the weekend, the Dragons still finished second in their group by virtue of a superior goal difference compared to Switzerland’s.
That result has seen Wales move into the perhaps more favourable bottom half of the draw, with the top half containing the likes of France, Portugal, Belgium, Italy and Spain.
Victory over Denmark on Saturday would see the Welsh head back to Baku for a third game in the Azeri capital, against either the Netherlands or the Czech Republic on July 3.
Win that quarter-final and Page’s men would find themselves in the semi-finals at Wembley, possibly against England should Gareth Southgate’s men progress to that stage.