Fabianski, who missed last weekend’s game at Manchester City after his arm was stood on in training, is back – but the Pole has not had a full day of training since.
Darren Randolph stood in at The Etihad but suffered a recurrance of a hip injury, meaning third choice David Martin s on the bench.
The Hammers dropped out of the top four thanks to wins from Chelsea and Everton midweek and will be keen to keep pace in the race for the top four.
West Ham vs Leeds lineups
West Ham: Fabianski, Coufal, Dawson, Diop, Cresswell, Soucek, Rice, Fornals, Lingard, Benrahma, Antonio
Subs: Balbuena, Lanzini, Noble, Bowen, Martin, Johnson, Trott, Odubeko
Leeds: Meslier, Ayling, Llorente, Cooper, Dallas, Phillips, Raphinha, Klich, Roberts, Helder Costa, Bamford
Subs: Poveda-Ocampo, Alioski, Rodrigo, Harrison, Davis, Caprile, Jenkins, Huggins, Berardi